Learn more about Choline uses, effectiveness, possible side effects, CHOLINE. OTHER NAME(S). Bitartre de Choline, Chlorure de Choline, Choline. Structure, properties, spectra, suppliers and links for: choline chloride, chlorure de choline [French] [INN]. choline chloride [INN]. More CHOLINE. Choline chloride ≥99%; CAS Number: ; EC Number: ; Synonym: (2-Hydroxyethyl)trimethylammonium chloride; Linear Formula: C5H14ClNO;.

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Choline chloride is an organic compound and a quaternary ammonium salt, an acyl cohline acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens wh ere it accelerates growth.

Preliminary clinical research suggests that taking choline orally may reduce manic symptoms and other mood symptoms in some lithium-treated patients with rapidly cycling bipolar disorder compared to chlline There is some evidence that higher doses of 3 grams daily might be more effective than lower doses of 1. Incompatible with strong oxidizing agents, moisture. Taking choline orally does not improve memory in elderly people with chhlorure loss Although closely related, these terms are not synonymous.

Ullmann’s Encyclopedia of Industrial Chemistry. Effort is made to ensure that the information contained in this Natural Medicines monograph is accurate at the time it was published.

choline chloride | C5H14ClNO | ChemSpider

Human breast milk contains choline. Typically, doses above 3. Infant and child development. Some researchers are interested in choline for Alzheimer’s disease because it fholine a precursor to acetylcholine. It is a white, water soluble salt used mainly in animal feed.

Chlorure de choline

Orally, adverse reactions can include sweating, a fishy body odor, gastrointestinal distress, and vomiting Web-based Article blog or commentary. An average diet supplies mg of choline daily Ethanaminium, 2-hyd roxy-N,N,N-trimethy l- chloride 1: Trimethylethanolaminebeta-hydroxyethyl trimethylammonium hydroxide.


For asthma, mg three times daily has been used Adding choline to the TPN solution usually improves liver function Foods that supply large amounts of choline are liver, muscle meats, fish, nuts, beans, peas, eggs, wheat germ, spinach, and others. Other commercial choline salts are choline hydroxide and choline bitartrate. See separate listings for Phosphatidylcholine and Lecithin. May irritate eyes, skin, and respiratory tract Alfa Aesar A A legal License Agreement sets limitations on downloading, storing, or printing content from Natural Medicines.

choline chloride (CHEBI)

However, we cannot guarantee the information is error-free and disclaim any liability or responsibility for chollne reliance on it. Adequate Intake AIas established by the Chporure and Nutrition Board of the National Institute of Medicine, for adults is mg per day for males and lactating women; females, mg per day; pregnant females, mg per day Epidemiological evidence suggests that women who have a high dietary choline intake around the time of conception have a lower risk of having offspring with a neural tube defect compared to women with lower intake This might be the reason oral cholind does not seem to be effective for neurodegenerative disorders of cholinergic transmission Subscribe now so you can enter the Natural Medicines Comprehensive Database.

A typical diet provides mg daily.

Choline is added to infant formulas made from cow milk and soy Also, taking choline prior to participating in exhaustive, load-carrying exercise does not improve dexterity, upper or lower body strength, grip strength, or run time-to-exhaustion cholkne exercise compared to placebo S-adenosylmethionine is the methyl donor for this reaction However, this is controversial because dholine can be synthesized by the human body However, it may increase plasma free choline levels in some older children with this condition Large doses can cause diarrhea It is also used as a clay control additive in fluids used for hydraulic fracturing.


In animal models, long-term withdrawal of choline from the diet can cause hepatocarcinoma Preliminary clinical research shows that giving liquid choline chloride Vitamin Research Products orally at doses to achieve adequate intake AI daily for weeks does not increase plasma choline levels in infants with choline deficiency due to intestinal failure.

Preliminary clinical research suggests that taking choline as tricholine citrate mg daily for 8 weeks is less effective than intranasal budesonide mcg twice daily for reducing symptoms of allergic rhinitis Ethanaminium, 2-hyd roxy-N,N,N-trimethy l- chloride.

Choline chloride

Taking choline orally seems to decrease the severity of symptoms, the number of symptomatic days and the need to use bronchodilators in patients with asthma There is insufficient reliable information available about the safety of choline used in higher doses in pregnant or lactating women. Rule of 5 Violations: Choline deficiency, related to long-term TPN use, can result in increased alanine aminotransferase ALT and fatty liver.

Choline is also readily available in the typical diet Taking choline orally does not seem to be effective for delaying fatigue in endurance sports Choline also seems to play a role in the development of neural tube defects Journal Publishers via MeSH. However, another observational study shows that higher maternal and cord blood levels of choline during the first, second, or third trimester of pregnancy are not associated with improved intelligence in the child at 5 years of age Preliminary clinical research shows that taking choline bitartrate providing choline mg orally daily for 9 months does not improve global cognitive development or hippocampal-dependent memory compared to placebo in children aged 2.